Organic & Medicinal Chemistry Division

Vision

The chemistry department aims at the study of chemical and biological problems through an integrated effort entailing discovery of new molecules from plants, development of synthetic strategies for complex molecules, studies on nanoscopic materials and reactions in organized media, and biophysical study of the interaction of biological macromolecules. Alongside, the department seeks to participate in the development of drugs and other important biomolecules through active collaboration with industrial and institutional partners.

Objectives

  • To develop strategies for the synthesis of chiral cyclic ethers, amines and RNA analogs from carbohydrate derivatives.
  • To develop new synthetic methodologies, and synthesize heterocyclic compounds for screening biological activities.
  • To establish methodologies for carbohydrate-derived structurally unique nucleosides.
  • To develop and commercialize herbal medicines and other bioactive molecules.
  • To synthesize oligosaccharides and neo-glycoproteins as vaccine candidates, and carry out structural studies on pathogenic bacterial lipopolysaccharides relevant to glycobiology and glycoscience.
  • To design and synthesize medium ring heterocycles as potential anti-cancer, anti-hyperlipidemic and antimicrobial agents.
  • To develop methodologies for the synthesis of anti-leishmanial and anti-encephalitis compounds based on quinolines.
  • To design and synthesize novel chiral surfactants for exploring new reaction systems and reagents for carrying out selective organic reactions in organized media.
  • To study nanoscopic materials such as stabilized nanoparticles and nanofibers.
  • To isolate and characterize bioactive substances from medicinal plants.
  • To understand the mode, mechanism, sequence specificity and energetics of binding of alkaloids and other natural products to polymorphic nucleic acid structures.

 


   © CSIR-IICB, Kolkata     Designed and Maintained by Computer Division ,CSIR - IICB