Structural Biology & Bio-Informatics Division

Dr. Sucheta Tripathy

Principal Scientist, Ramalingaswamy Fellow, Associate Professor (AcSIR)

Ph.D Plant Molecular Biology 1998 (Center For Plant Molecular Biology, Hyderabad)
Training in Software Technology for PGDST at NCST(Now cDAC, dept. of science and Technology), Mumbai,2000
Bioinformatics Training, DSQ Biotech, Chennai, India, 2000

Professional Preparation:
Lecturer at Ratnam College, Mumbai University (1998-2000)
Scientist (Bioinformatics division) at DSQ biotech limited (2000-2001)
Scientist and Head Bioinformatics division at Avesthagengrain Pvt. Ltd.(2001-2002)
Senior scientist and Bioinformatics Team lead at Virginia Bioinformatics Institute at Virginia tech (2002-2012)


Contact - /

Room-248, 246.
Phone: 913324995894 (direct lab)


Additional Info:


Current Research Interest

My lab is currently interested in the following research areas:

  1. Can we predict transcript expression of a given cell line under a given condition by using existing data such as transcription factor binding sites, CAGE tag data, epigenetic data and physical structure of DNA?
  2. How to exploit the non-ribosomal protein synthetic pathway for over production of bio-active and bio-energy compounds from photosynethic prokaryotes using nextgen genomics.
  3. Nextgen genomics data dissemination and portrayal using efficient data structures and schemas.
  4. Development of novel algorithms and softwares for genome and transcriptome assembly and annotation.

Names of the group members including regular staff with designation and research fellows

Our Research Team:

  • Diya Sen: RA, CSIR.
  • Rajib Majumdar: RA, CSIR
  • Lubna Sheikh : SRF, DST.
  • Subhadeep Das: SRF, DBT.
  • Abhishek Das: SRF, ICMR.
  • Mathu Malar C.: SRF, DST.
  • Arijit Panda: SRF, CSIR-NET.
  • Deeksha Singh: SRF, ICMR
  • Pijush Das, SRF: CSIR
  • Mayuri Mukherjea: JRF, CSIR
  • Samrat Ghosh: JRF, DBT
  • Vineeta Vinni: RA, ICAR
  • Md. Shamsul Haque: Supporting staff.

Currently positions open for Engg. Graduates/programmers having a research fellowship.

1. Manipulating the genomes of Cyanobacteria and metabolic re-engineering.
2. Programmers for upgrading into an analytic platform..

If you are having a fellowship and have good logical reasoning, creativity, theoretical knowledge, practical skills, motivation, communication skills and you are a team player as well as capable of handling projects independently, write to me directly.



List of important Publications

Publications from IICB:

  1. Das A, Panda A, Singh D, Chandrababunaidu MM, Mishra GP, Bhan S, Adhikary SP, Tripathy S*. Deciphering the Genome Sequences of the Hydrophobic Cyanobacterium Scytonema tolypothrichoides VB-61278. Genome Announc. 2015 Apr 2;3(2). pii:e00228-15. doi: 10.1128/genomeA.00228-15. PubMed PMID: 25838486.
  2. Das S, Singh D, Madduluri M, Chandrababunaidu MM, Gupta A, Adhikary SP,Tripathy S*. Draft Genome Sequence of Bioactive-Compound-Producing Cyanobacterium Tolypothrix campylonemoides Strain VB511288. Genome Announc. 2015 Apr 2;3(2). pii: e00226-15. doi: 10.1128/genomeA.00226-15. PubMed PMID: 25838485.
  3. Chandrababunaidu MM, Sen D, Tripathy S*.. Draft Genome Sequence of Filamentous Marine Cyanobacterium Lyngbya confervoides Strain BDU141951. Genome Announc. 2015 Mar 5;3(2). pii: e00066-15. doi: 10.1128/genomeA.00066-15. PubMed PMID: 25745003
  4. Singh D, Chandrababunaidu MM, Panda A, Sen D, Bhattacharyya S, Adhikary SP,Tripathy S*. Draft Genome Sequence of Cyanobacterium Hassallia byssoidea Strain VB512170, Isolated from Monuments in India. Genome Announc. 2015 Mar 5;3(2). pii:e00064-15. doi: 10.1128/genomeA.00064-15. PubMed PMID: 25745001
  5. Bhattacharyya S, Chandrababunaidu MM, Sen D, Panda A, Ghorai A, Bhan S, Sanghi N, Tripathy S*. Draft Genome Sequence of Exopolysaccharide-Producing Cyanobacterium Aphanocapsa montana BDHKU 210001. Genome Announc. 2015 Mar 5;3(2).pii: e00057-15. doi: 10.1128/genomeA.00057-15. PubMed PMID: 25744997.
  6. Sen D, Chandrababunaidu MM, Singh D, Sanghi N, Ghorai A, Mishra GP, Madduluri M, Adhikary SP, Tripathy S*. Draft Genome Sequence of the Terrestrial Cyanobacterium Scytonema millei VB511283, Isolated from Eastern India. Genome Announc. 2015 Mar 5;3(2). pii: e00009-15. doi: 10.1128/genomeA.00009-15. PubMed PMID: 25744984.
  7. Chandrababunaidu MM, Singh D, Sen D, Bhan S, Das S, Gupta A, Adhikary SP, Tripathy S*. Draft Genome Sequence of Tolypothrix boutellei Strain VB521301.Genome Announc. 2015 Feb 19;3(1). pii: e00001-15. doi: 10.1128/genomeA.00001-15.PubMed PMID: 25700407; PubMed Central PMCID: PMC4335316.
  8. A Tale of Effectors; Their Secretory Mechanisms and Computational Discovery in Pathogenic, Non-Pathogenic and Commensal Microbes.S Bhowmick, S Tripathy* - Mol Biol, 2014. 3 (118), 2
  9. Bhowmick S, Malar M, Das A, Kumar Thakur B, Saha P, Das S, Rashmi HM, Batish VK, Grover S, Tripathy S*. Draft Genome Sequence of Lactobacillus casei Lbs2.Genome Announc. 2014 Dec 24;2(6). pii: e01326-14. doi: 10.1128/genomeA.01326-14.PubMed PMID: 25540344; PubMed Central PMCID: PMC4276822.

Book Chapter:

  1. Tripathy S., Deeksha Singh, Mathu Malar C. and Abhishek Das. Dissecting Transcriptomes of Cyanobacteria for novel metabolite production. Willey Interscience [In Press]

Publications prior to joining IICB:

  1. Jiang RH, de Bruijn I, Haas BJ, Belmonte R, Löbach L, Christie J, van denAckerveken G, Bottin A, Bulone V, Díaz-Moreno SM, Dumas B, Fan L, Gaulin E,Govers F, Grenville-Briggs LJ, Horner NR, Levin JZ, Mammella M, Meijer HJ, Morris P, Nusbaum C, Oome S, Phillips AJ, van Rooyen D, Rzeszutek E, Saraiva M, Secombes CJ, Seidl MF, Snel B, Stassen JH, Sykes S, Tripathy S, van den Berg H, Vega-Arreguin JC, Wawra S, Young SK, Zeng Q, Dieguez-Uribeondo J, Russ C, Tyler BM, van West P. Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasitica. PLoS Genet. 2013 Jun;9(6):e1003272. doi: 10.1371/journal.pgen.1003272. Epub 2013 Jun 13. PubMed PMID: 23785293; PubMed Central PMCID: PMC3681718. [JIF: 8.167]
  2. Tripathy,S*., Tejal Deo, Brett M Tyler (2012)  Oomycete transcriptomics database: A resource for oomycete transcriptomes.   BMC Genomics.[JIF: 4.2][Highly accessed]
  3. Tripathy, S*., Rays H Y Jiang (2012)  Massively parallel sequencing technology in pathogenic microbes.   Methods Mol Biol 835: 271-294. [JIF: 13.9]
  4. Qunqing Wang1, Changzhi Han1, Adriana Ferreira2, Wenwu Ye1, Tripathy, S.,2, Shiv Kale2, Biao Gu2,3, Xiaoli Wang1, Xiaoli Yu1, Tiuli Liu1, Yao Yao1, Xinle Wang1, Zhengguang Zhang1, Baoping Cheng1, Suomeng Dong1, Weixing Shan3, Xiaobo Zheng1, Daolong Dou1,2, Brett M. Tyler2,4 and Yuanchao Wang1,4   Transcriptional programming and functional interactions within the Phytophthora sojae RXLR effector repertoire. Plant Cell 2011 23:2064-2086l (Featured in cover of Plant Cell, August 2011). [JIF: 10.68]
  5. Laura Baxter, Tripathy, S., et al., [Joint First Author]  Signatures of adaptation to obligate biotrophy in the Hyaloperonospora arabidopsidis genome. Science 10 December 2010: 1549-1551.Featured in science cover  [JIF: 31.364]
  6. C. André Lévesque, Henk Brouwer, Liliana Cano, John P. Hamilton, Carson Holt, Edgar Huitema, Sylvain Raffaele, Gregg P. Robideau, Marco Thines, Joe Win, Marcelo M Zerillo, Gordon W. Beakes, Jeffrey L. Boore, Dana Busam, Bernard Dumas, Steve Ferriera,Susan I. Fuerstenberg, Claire MM Gachon, Elodie Gaulin, Francine Govers, Laura Grenville-Briggs, Neil Horner, Jessica Hostetler, Rays H.Y. Jiang, Justin Johnson, Theerapong Krajaejun,Haining Lin, Harold J.G. Meijer, Barry Moore, Paul Morris, Vipaporn Phuntmart, Daniela Puiu,Jyoti Shetty, Jason E. Stajich, Tripathy, S.,, Stephan Wawra, Pieter van West, Brett R.Whitty, Pedro M. Coutinho, Bernard Henrissat, Frank Martin, Paul D. Thomas, Brett M. Tyler,Ronald P. De Vries, Sophien Kamoun, Mark Yandell, Ned Tisserat, and C. Robin Buell(2010). Genome sequence of the necrotrophic plant pathogen, Pythium ultimum,reveals original pathogenicity mechanisms and effector repertoire. Genome Biology 2010 Jul 13;11(7):R73. [Epub ahead of print] PubMed PMID: 20626842. [JIF: 6.89]
  7. Wang, H., L. Waller, Tripathy, S.,, S.K. St. Martin, L. Zhou, K. Krampis, D.M. Tucker, Y. Mao, I. Hoeschele, M.A. Saghai Maroof, B.M. Tyler, and A.E. Dorrance. 2010. Analysis of Genes   Underlying Soybean QTL Conferring Partial Resistance to Phytophthora sojae. The Plant Genome 3: 23-40. . [JIF : 4.659]
  8. M. A. Saghai Maroof, Dominic M. Tucker, Jeffrey A. Skoneczka, Brian C. Bowman, Tripathy, S.,, and Sue A. Tolin. 2010. Fine Mapping and Candidate Gene Discovery of the Soybean Mosaic Virus Resistance Gene, Rsv4Plant Gen. July 2010 3:14-22; doi:10.3835 The Plant Genome. 2009.07.0020 . [JIF: 4.659]
  9. Lecong Zhou, Santiago X. Mideros, Lei Bao, Regina Hanlon, Felipe Arredondo, Tripathy, S.,, Konstantinos Krampis, Adam Jerauld, Clive Evans, Steven K. St. Martin, Saghai M.A. Maroof, Ina Hoeschele, Anne E. Dorrance and Brett M. Tyler.(2008) Infection and Genotype Remodel the Entire Soybean Transcriptome. BMC Genomics. 2009 Jan 26;10(1):49 Highly accessed. [JIF : 4.21]
  10. Jiang RH, Tripathy S, Govers F, Tyler BM.(2008)RXLR effector reservoir in two Phytophthora species is dominated by a single rapidly evolving superfamily with more than 700 members. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4874-9. Epub 2008 Mar 14. . [JIF : 9.771]
  11. Trudy Torto-Alalibo1, Tripathy, S.,et. al. The Phytophthora sojae EST Dataset: A Resource for Gene Discovery Specific to Different Morphological and Infection Stages in P. sojae. Molecular Plant Microbial Interaction.2007. 20:781-793. . [JIF : 4.4]
  12. Brett M. Tyler,1, Tripathy, S.,,1 Xuemin Zhang,1et. al. Phytophthora Genome Sequences Uncover Evolutionary Origins and Mechanisms of Pathogenesis Genome sequences of the soybean pathogen Phytophthora sojae and the sudden oak death pathogen Phytophthora ramorum reveal a photosynthetic past and recent massive expansion and diversification of potential pathogenicity gene families. Science. 303: 1261-1265,2006. [JIF : 31.364]
  13. Tripathy S*, Tyler BM (2006).  The repertoire of transfer RNA genes is tuned to codon usage bias in the genomes Phytophthora sojae and Phytophthora ramorum. Mol. plant-Microbe Interact. 19(12):1329-1336 [JIF:  4.4]
  14. Tripathy, S.,, V. N. Pandey, B. Fang, F. Salas, B. M. Tyler; VMD a community annotation database for oomycetes and microbial genomes. Nucleic Acids Res. 34. D379-D381, 2006. Featured in Science Netwatch. [JIF: 8.808]
  15. Zhang X, Scheuring C, Tripathy S et al.,(2006) An integrated BAC and genome sequence physical map of Phytophthora sojae. Mol. Plant-Microbe Interact. 19(12): 1302-1310. [JIF: 4.4]
  16. Tyler, Brett; Tripathy, S., Grunwald, Nik; Lamour, Kurt; Ivors, Kelly; Garbelotto, Matteo; Rokhsar, Daniel; Putnam, Nik; Grigoriev, Igor; Boore, Jeffrey  2006.  Genome sequence of Phytophthora ramorum: implications for management.   In: Frankel, Susan J.; Shea, Patrick J.; and Haverty, Michael I., tech. coords. Proceedings of the sudden oak death second science symposium: the state of our knowledge. Gen. Tech. Rep. PSW-GTR-196. Albany, CA: Pacific Southwest Research Station, Forest Service, U.S. Department of Agriculture: 157-158. [JIF : undetermined]
  17. Tripathy, S*.,, G.M.Reddy; In Vitro Callus Induction and Plantlet Regeneration from Indian Cotton Cultivars, Plant Cell Biotechnology and Molecular Biology. An International Journal on Biotechnological Research, 3&4:137-142, 2002, [JIF : undetermined]
  18. Tripathy, S*.,, G.M.Reddy; A study on the influence of genotype, medium and additives on the induction of multiple shoots in Indian cotton cultivars; Asian Journal of Microbiology, Biotechnology & Environmental Sciences, 4:515-519, 2002. [JIF : undetermined]

Book chapters

  1. Tripathy, S.* (2011)  Cancer and Diet   In: Herbal perspectives Edited by:T. Parimelazhagan, S. Manian and M. Pugalenthi, Satish Serial. 486 isbn:8189304917
  2. Brett M. Tyler4, Rays H.Y. Jiang, Lecong Zhou, Tripathy, S.,, Daolong Dou, Trudy Torto-Alalibo, Hua Li, Yongcai Mao, Bing Liu, Miguel Vega-Sanchez, Santiago X. Mideros, Regina Hanlon, Brian M. Smith, Konstantinos Krampis, Keying Ye, Steven St. Martin, Anne E. Dorrance, Ina Hoeschele and M.A. Saghai Maroof(2008) Functional Genomics and Bioinformatics of the Phytophthora sojae Soybean Interaction.ISSN:1568-1009,ISBN:978-0-387-76722-2 (Print) 978-0-387-76723-9 (Online)

[* - corresponding author]


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