Saraswati Garai , Ph.D.

Scientist
Organic & Medicinal Chemistry
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Research Interest

Isolation and characterization of natural products from the Indian Medicinal Plants and their pharmacological and biological activities and also commercialization.

Credentials

  • Scientist, CSIR-IICB,  (2009-still now)
  • Scientist B,  CSIR-IICB, Kolkata (October 23, 2007-2008) 
  • Scientist B,  RRL(IIIM), Jammu (2004 - October 22, 2007) 
  • Postdoctoral Research Fellow, Tokushima Bunri University, Japan (1998 –1999),  Prof. M. Nishizawa
  • Ph.D, Organic Chemistry, CSIR-IICB, (1993-1997), Dr. S. B. Mahato  

Honours & Awards

  • Junior Research Fellowship (CSIR) 1991 & 1992
  • IISC Bangalore Ph.D Admission Test 1992
  • Research Associateship (CSIR) 1997
  • Senior Research Associateship (CSIR) 2002
  • Recipient of the Merit Certificate in Chemistry of Indian Science Congress Association’s (ISCA) Young Scientist’s Award programme in January 8, 1997.
  • The International Symposium on Current Status and Opportunities in Aromatic and Medicinal Plants (February 21-24, 2010) “Corrosion inhibition of mild steel by bacopasaponins” one of the best of 2 posters in the session on “ Session IV : IPR Industrial and ethical issues”
  • Life Membership of Indian Science Congress Association (1996-present)
  • Life Memerbership of Association of Carbohydrate Chemists & Technologists (India) (2011-present)

Grant Supports

  • CSIR NETWORK PROJECT 2004-2006, RRL(IIIM), Jammu
  • CSIR NETWORK PROJECT 2007-2011, CSIR-IICB, Kolkata
  • CSIR NETWORK PROJECT (ORIGIN) 2012-2017, CSIR-IICB, Kolkata
  • IN HOUSE PROJECT, CSIR-IICB, Kolkata (December, 2012-2017)

Patents & Publications

  1. BANDHOPADHYAY A, S. GARAI, PP. BANDHOPADHYAY, S. BHATTACHARYA, A. CHATTOPADHYAY, Evaluation of the Anti-cancer effect of of Bacopa monniera - derived dammarane saponins in human breast cancer cell lines. Int. J. Herbal Medicine. 7, 39(2019).
  2. GARAI S, Discovery of Triterpenoid Saponins Research 2013-2016. Journal of Herbal Medicine, (2018) (Revision).
  3. GARAI S, R. GHOSH, PP. BANDHOPADHYAY, NC. MANDAL, A. CHATTOPADHYAY. Anti-microbial and Anti-cancer Properties of  Echinocystic Acid Extracted from Luffa cylindrica. J.Food.Process.Technol. 2018, 9. 2. DOI:10.4172/2157-7110.1000717.
  4. GARAI S, Advances in Triterpenoid Saponins Research, Journal of Herbal Medicine,  Vol.1 No. 3: 14(2016).  DOI: 10.21767/2472-0151.100020.
  5. GARAI S, Triterpenoid saponins, Natural Product Research & Chemistry,  1-13(2014).
  6. GARAI S, S. GARAI. Corrosion inhibition of mild steel in acid solution by bacopasaponins from Bacopa monniera. The International Symposium on Current Status & Opportunities in Aromatic & Medicinal Plants (Abstract) (2010).
  7. MAZUMDAR S, S. GARAI and S. JHA. Use of the cryptogein gene to stimulate the accumulation of bacopasaponins in transgenic Bacopa monnieri plants. Plant Cell Reports. 31, 1899(2012).  
  8. GARAI S, SARASWATI  GARAI, P. JAISANKAR, J. K.SINGH and A. ELANGO. A comprehensive study on crude methanolic extract of Artemisia pallens (Asteraceae) and its active component as effective corrosion inhibitors of mild steel in acid solution. Corrosion Science 60, 193 (2012).
  9. MAZUMDAR, S, S. GARAI and S. JHA. Genetic transformation of Bacopa monniera by wild type strains of Agrobacterium rhizogenes stimulates   production of bacopasaponins in  transformed calli and plants.  Plant Cell Reports 30, 941(2011). 
  10. KHAJURIA, A., A. GUPTA, S. GARAI and B. P. WAKHLOO : Immunomodulatory effects of two sapogenins 1 & 2 isolated from Luffa cylindrica  in bulb/C mice. Bioorganic & Medicinal Chemistry Letter , 17, 1608(2007).
  11. CHAKRAVARTY, A. K., S. GARAI, MASUDA, K and NAKANE, T : Bacopaside III-V : Three more triterpenoid glycosides from Bacopa monniera. Chem. Pharm. Bull. 51, 215(2003).  
  12. SINHA, J., B. RAAY, N. DAS, S. MEDDA, S. GARAI, S. B. MAHATO and M. K. BASU : Bacopasaponin C : Critical Evaluation of Anti-Leishmanial Properties in various Delivery Modes. Drug Delivery 9, 1(2002).
  13. MAHATO, S. B., S. GARAI and A. K. CHAKRAVARTY ; Two Dammarane – type bisdesmosides from Bacopa monniera. Phytochemistry 53, 711(2000).
  14. GARAI, S. Synthesis of Alnustic acid glycosides (Abstract) ( Conference in Japan 1999)
  15. GARAI, S., S. B. MAHATO : Isolation and structure elucidation of three triterpenoid saponins from Acacia auriculiformis. Phytochemistry 44, 137(1997).
  16. GARAI, S., S. B. MAHATO, K. OHTANI and K. YAMASAKI : Bacopasaponin D- A pseudojujubogenin glysoside from Bacopa monniera. Phytochemistry 43, 447(1996).
  17. GARAI, S., S. B. MAHATO, K. OHTANI and K. YAMASAKI : Dammarane – type triterpenoid saponins from Bacopa monniera. Phytochemistry 42, 815(1996).

 

BOOK CHAPTER

  1. MAHATO, S. B., GARAI, S. : Triterpenoid saponins, Progress in the Chemistry of  Organic Natural products Herz W., Kirby, G. W. Moore, R. E., Steglich W and Tamm, Ch. Eds. Vol. 74, 1-196, Springer, Wien, New York (1998).