Parasuraman Jaisankar

Dr. Parasuraman Jaisankar

Chief Scientist

Ph.D. Jadavpur University, 1995,
Raman Research Fellow – Prof. M. Kitamura, Nagoya University, Japan (2010),
RCMS Fellow – Nobel Laureate Prof. R. Noyori, & Prof. M. Kitamura, Japan (2001-02),
DAAD Fellow – Ulm University, Germany (1996-98).

+91 33 24995790
    1. Development of chiral ligands and their transition metal complexes for asymmetric organic transformations.
    2. Synthesis of Lead Compounds and their analogues having various biological activities, with special focus on anticancer and anti-asthmatic, anti-microbial, and anti-inflammatory compounds.
    3. Development of synthetic strategy for the generation of structurally unique bioactive molecules especially nitrogen heterocycles.
    4. Identification and structure elucidation of antibiotics isolated from marine actinobacterium.Search for safe drugs from herbal sources.
    1. Parasuraman Jaisankar, Tanaka S, Kitamura M. Catalytic Dehydrative S-Allylation of Cysteine Containing Peptides in Aqueous Media toward Lipopeptide Chemistry. J. Org. Chem. 76, 1894-1897 (2011).
    2. Regioselective One Pot Synthesis of 3, 3′-Diindolylethylene Derivatives and Study of their Cytotoxic activity, Madhumita Mandal, Deepak Kumar, Rajneeta Roy, Rupashree Sen, Padma Das, Mitali Chatterjeec and Parasuraman Jaisankar, Bioorganic & Medicinal Chemistry Lett. 21, 3084-3087 (2011).
    3. 2-Methyl-pyran-4-one-3-O-β-d-glucopyranoside isolated from leaves of Punica granatum inhibits the TNFα-induced cell adhesion molecules expression by blocking nuclear transcription factor-κB (NF-κB), Sakshi Balwani, Debkumar Nandi, ParasuramanJaisankar and Balaram Ghosh, Biochimie,93, 921-930 (2011).
    4. Lewis Acid-Catalyzed One-Pot, Three-Component Route to Chiral 3,3′-Bipyrroles:  Dey, S., Pal, C., Nandi, D., Giri, V. S., Zaidlewicz, M., Krzeminski, M., Smentek, L., Hess, B. A., Gawronski, J., Kwit, M., Babu, N. J., Nangia, A., and Jaisankar, P. Organic  Lett., 10(7), 1373 – 1376 (2008).
    5. Mitochondria dependent ROS-mediated programmed cell death (PCD) induced by 3,3′-Diindolylmethane (DIM) through Inhibition of FoF1-ATP synthase in unicellular protozoan parasite Leishmania donovani: A. Roy, A. Ganguly, S. BoseDasgupta, B. B. Das, C. Pal, P. Jaisankar, H. K. Majumder, Molecular Pharmacology, 74 (5), 1292-1307 (2008).
    6. Asymmetric synthesis of N-1-(heteroaryl)ethyl-N-hydroxyureas: Mariusz J. Bosiak, Marek P. Krzemiński, P. Jaisankar and Marek Zaidlewicz, Tetrahedron: Asymmetry, 19, 956-963 (2008).
    7. Asymmetric synthesis of N-substituted N-hydroxyureas: Krzysztof Z. Łączkowski, Marcin M. Pakulski, Marek P. Krzemiński, P. Jaisankar and Marek Zaidlewicz, Tetrahedron: Asymmetry, 19, 788-795 (2008).
    8. Indium trichloride catalyzed efficient one-pot synthesis of highly substituted Furans: S. Dey, D. Nandi, P. K. Pradhan, V. S. Giri and P. Jaisankar, Tetrahedron Lett. 48, 2573-2575 (2007).
    9. Eco-friendly synthesis and study of new plant growth promoters: 3,3´- Diindolylmethane and its derivatives: C. Pal, S. Dey, S. K. Mahato, J. Vinayagam, P. K. Pradhan, V. S. Giri, P. Jaisankar, T. Hossain, S. Baruri, D. Ray and S. Mandal Biswas, Bioorganic & Medicinal Chemistry Lett. 17, 4924-4928 (2007).
    10. InCl3-HMTA as a Methylene Donor: One-Pot Synthesis of Diindolylmethane (DIM) and its Derivatives, P. K. Pradhan, S. Dey, V. S. Giri, and P. Jaisankar, Synthesis, 1779-1782 (2005).
    11. First Indium Trichloride Catalyzed Self-addition of Indoles: One Pot Synthesis of Indolylindolines, B. Pal, V. S. Giri, and P. Jaisankar, Catalysis Commun. 6, 711-715 (2005).
    12. Unusual Formation of Chiral b-Carboline Dimers Under Bischler-Napieralski Reaction Conditions: An Old Reaction With A New Direction: B. Pal, P. Jaisankar, and V. S. Giri, Tetrahedron Lett. 45, 6489-6492 (2004).
    13. Selective Reduction of Aldehydes to Alcohols Using Alumina with a Catalytic amount of Base Under Microwave Irradiation: P. K. Pradhan, P. Jaisankar, B. Pal, S. Dey, and V. S. Giri, Synth. Commun, 35, 2863-2872 (2004).
    14. Versatile Reagent for Reduction of Azides to Amines: B. Pal, P. Jaisankar, V. S. Giri, Synth. Commun, 34, 1317 (2004).
    15. First Triphenylphosphine Promoted Reduction of Maleimides to Succinimides: B. Pal, P. K. Pradhan, P. Jaisankar, and V. S. Giri, Synthesis, 1549 (2003).
    16. Synthetic studies in Indoloquinolizidine system: V. S. Giri, P. Jaisankar, R. K. Manna, J. N. Shoolery, P. Keifer, Tetrahedron, 51, 10101 (1995).
    17. Unusual formation of a Novel Pyrrolo[1′,2′:1,2]pyrido[3,4]-indole, V. S. Giri, S. K. Das and P. Jaisankar, J. Heterocyclic  Chemistry, 29, 767 (1992).
    18. Synthesis of alkaloids (±)-Deplancheine and Flavopereirine, P. Jaisankar, S. K. Das and V. S. Giri, Heterocycles, 32, 1109 (1991).