Dr. Uday Bandyopadhyay
Senior Principal Scientist
Ph.D Jadavpur University, Calcutta, (1994)
J.C. Bose National Fellow
Fellow of Indian National Science Academy (FNA)
Fellow of Indian Academy of Sciences (FASc)
Fellow of The National Academy of Sciences, India (FNASc)
INSERM Fellow , Paris, France
Humboldt Fellow (Alexander Von Humboldt Foundation,), Germany
Fellow of the West Bengal Academy of Science and Technology (FAScT)
- Gastric ulcer and free radical biology:
- Gastric mucosal cell signaling, apoptosis, mitochondrial biology and dynamics.
- Wound healing, cell growth and proliferation
- The exploration of Plasmodium falciparum proteome to identify new drug target.
- Epigenetic and molecular biology of malaria parasite.
- Host- parasite interaction.
- Gastric ulcer and free radical biology:
- Mohd. Shameel Iqbal (SRF)
- Souvik Sarkar (SRF)
- Somnath Mazumder (JRF)
- Asim Azhar Siddiqui (JRF)
- Chinmoy Banerjee (JRF)
- Rudranil Dey (JRF)
- Shubhra Jyoti Saha (JRF)
Identification and molecular characterization of an Alba-family protein from human malaria parasite Plasmodium falciparum. Goyal M, Alam A, Iqbal MS, Dey S, Bindu S, Pal C, Banerjee A, Chakrabarti S, Bandyopadhyay U. Nucleic Acids Res. 2012 Feb 1;40(3):1174-90.
Impact of Intravascular Hemolysis in Malaria on Liver Dysfunction: Involvement of Hepatic Free Heme Over-load, NF Activation and Neutrophil Infiltration. Sumanta Dey, Samik Bindu, Manish Goyal, Chinmay Pal, Athar Alam, Mohd. Shameel Iqbal, Rahul Kumar, Souvik Sarkar, and Uday Bandyopadhyay. J. Biol. Chem. 2012 Aug 3; 287(32):26630-46.
Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and pro-inflammatory activities of macrophage migration inhibitory factor. Alam A, Haldar S, Thulasiram HV, Kumar R, Goyal M, Iqbal MS, Pal C, Dey S, Bindu S, Sarkar S, Pal U, Maiti NC, Bandyopadhyay U. J. Biol. Chem. 2012 Jul 13;287(29):24844-61.
Tryptamine-gallic acid hybrid prevents non-steroidal anti-inflammatory drug-induced gastropathy: Correction of mitochondrial dysfunction and inhibition of apoptosis in gastric mucosal cells. Pal C, Bindu S, Dey S, Alam A, Goyal M, Iqbal MS, Sarkar S, Kumar R, Halder KK, Debnath MC, Adhikari S, Bandyopadhyay U. J Biol Chem. 2012 Jan 27;287(5):3495-509.
Translocation of heme oxygenase-1 to mitochondria is a novel cytoprotective mechanism against non-steroidal anti-inflammatory drug-induced mitochondrial oxidative stress, apoptosis and gastric mucosal injury. Bindu S, Pal C, Dey S, Goyal M, Alam A, Iqbal MS, Dutta S, Sarkar S, Kumar R, Maity P, Bandyopadhyay U. J Biol Chem. 286, 39387-39402, 2011.
Cysteine-3 and cysteine-4 are essential for the thioredoxin-like oxidoreductase and antioxidant activities of Plasmodium falciparum macrophage migration inhibitory factor. Alam A, Goyal M, Iqbal MS, Bindu S, Dey S, Pal C, Maity P, Mascarenhas NM, Ghoshal N, Bandyopadhyay U. Free. Radic. Biol. Med , 50 (2011) 1659–1668.
Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: A novel role of mitochondrial aconitase oxidation. Maity P, Bindu S, Dey S, Goyal M, Alam A, Pal C, Mitra K, Bandyopadhyay U. J. Biol. Chem. 284: (2009),3058-3068.
Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathway with concurrent induction of mucosal cell renewal. P Maity, S. Bindu,V Choubey, A. Alam, K. Mitra, M. Goyal, S. Dey, M Guha, C. Pal and U Bandyopadhyay. J. Biol. Chem , 283 : (2008), 14391-14401.
Apoptosis in liver during malaria: Role of oxidative stress and implication of mitochondrial pathway. Mithu Guha, Sanjay Kumar, Vinay Choubey, Pallab Maity and Uday Bandyopadhyay (2006). FASEB. J, 20, 1224-1226.
Clotrimazole Inhibits Hemo- peroxidase of P. falciparum and Induces Oxidative Stress: PROPOSED ANTIMALARIAL MECHANISM OF CLOTRIMAZOLE. Vishal Trivedi ,Prem Chand, Kumkum Srivastava, Sunil K. Puri, Prakas R. Maulik, and Uday Bandyopadhyay (2005) J. Biol. Chem. 280, 41129-41136.