Ratanti Sarkhel, B.VSc & AH, M. VSc, Ph.D

Scientist
Cell Biology & Physiology
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Research Focus

1. Biochemical basis of host pathogenic interaction during stress and 2. Experiments in animal model

Research Interest

  1. Biochemical basis of host pathogenic interaction during stress
  2. Experiments in animal model

 

Credentials

  • Bachelors in Veterinary sciences & Animal Husbandry (B.VSc & AH), 2009-14, West Bengal University of Animal and Fisheries Sciences.
  • Masters in veterinary sciences (M.VSc) ICAR- JRF, 2014- 16, Animal Biochemistry, ICAR- Indian Veterinary Research Institute, Bareilly. 
  • Ph. D in Animal Biochemistry (ICMR SRF), 2016-21, Animal Biochemistry, ICAR- Indian Veterinary Research Institute, Bareilly.

 

Honours & Awards

  • Best oral presentation award, V11 Annual Convention Of SVBBI, held at ICAR- Indian Veterinary Research Institute, Bareilly (Dec 14- 15, 2023).
  • Best research paper award at ICAR-Indian Veterinary Research Institute, Bareilly (2017-18)
  • Received SERB- International travel grant to attend 6th Mediterranean Poultry Conference, Italy (2019)
  • Alembic Pharma’s Scholarship awarded on the basis of merit in B. VSc & AH                                                                                 
  • Gold Medalist for exceptional performance in B. VSc & AH from West Bengal University Of Animal & Fishery Sciences
  • ICAR NET 2017 in Animal Biochemistry (77.11 %)
  • ICMR JRF 2017

 

Patents & Publications

Publications:

  1. Sarkhel, R., Priyadarsini, S., & Mahawar, M. (2024) Nutrient limitation and oxidative stress induce the promoter of acetate operon in Salmonella Typhimurium. Archives of Microbiology. 206, 1-7. (https://pubmed.ncbi.nlm.nih.gov/38411730/)
  2. Sarkhel, R., Apoorva, S., Priyadarsini, S., Sridhar, H. B., Bhure, S. K., & Mahawar, M. (2022). Malate synthase contributes to the survival of Salmonella Typhimurium against nutrient and oxidative stress conditions. Scientific Reports, 12. [https://pubmed.ncbi.nlm.nih.gov/36155623/]
  3. Sarkhel, R., Rajan, P., Gupta, A. K., Kumawat, M., Agarwal, P., Shome, A., ... & Mahawar, M. (2017). Methionine sulfoxide reductase A of Salmonella Typhimurium interacts with several proteins and abets in its colonization in the chicken. Biochimica et Biophysica Acta (BBA)-General Subjects, 1861(12), 3238-3245. [https://pubmed.ncbi.nlm.nih.gov/28941926/]
  4. Kappala, D., Sarkhel, R., Dixit, S. K., Mahawar, M., Singh, M., Ramakrishnan, S., & Goswami, T. K. (2018). Role of different receptors and actin filaments on Salmonella Typhimurium invasion in chicken macrophages. Immunobiology, 223(6-7), 501-507. [https://pubmed.ncbi.nlm.nih.gov/29395289/]
  5. Nair, S. S., Chauhan, T. K. S., Kumawat, M., Sarkhel, R., Apoorva, S., Shome, A., ... & Mahawar, M. (2021). Deletion of both methionine sulfoxide reductase A and methionine sulfoxide reductase C genes renders Salmonella Typhimurium highly susceptible to hypochlorite stress and poultry macrophages. Molecular Biology Reports, 48(4), 3195-3203. [https://pubmed.ncbi.nlm.nih.gov/33954903/]
  6. Shome, A., Sarkhel, R., Apoorva, S., Nair, S. S., Chauhan, T. K. S., Bhure, S. K., & Mahawar, M. (2020). Role of protein repair enzymes in oxidative stress survival and virulence of Salmonella. Annals of Microbiology, 70, 1-10. [https://link.springer.com/article/10.1186/s13213-020-01597-2]
  7. Sarkhel, R., & Paul, A. (2018). Reverse vaccinology: the new trend in developing vaccines. Everyman’s science, 43. [https://sciencecongress.nic.in/pdf/e-book/Apr-May-2018.pdf#page=43]

 

Books:

  1. Paul, S., Chakraborty, S., Biswas, P., Mandal, A. K., Sadhukhan, T and Sarkhel, R. (2024) Vet – View, 1ST Edition, Astral International Pvt Ltd, India.
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