Organic & Medicinal Chemistry

To develop strategies for the synthesis of chiral cyclic ethers, amines and RNA analogs from carbohydrate derivatives.
To develop new synthetic methodologies, and synthesize heterocyclic compounds for screening biological activities.
To establish methodologies for carbohydrate-derived structurally unique nucleosides.
To develop and commercialize herbal medicines and other bioactive molecules.
To isolate and characterize bioactive substances from medicinal plants.
To design and synthesize medium ring heterocycles as potential anti-cancer, anti-hyperlipidemic and antimicrobial agents.
To synthesize oligosaccharides and neo-glycoproteins as vaccine candidates, and carry out structural studies on pathogenic bacterial lipopolysaccharides relevant to glycobiology and glycoscience.
To develop methodologies for the synthesis of anti-leishmanial and anti-encephalitis compounds based on quinolines.
To design and synthesize novel chiral surfactants for exploring new reaction systems and reagents for carrying out selective organic reactions in organized media.
To study nanoscopic materials such as stabilized nanoparticles and nanofibers.
To understand the mode, mechanism, sequence specificity and energetics of binding of alkaloids and other natural products to polymorphic nucleic acid structures.

Parasuraman Jaisankar

Chief Scientist & Head, Organic & Medicinal Chemistry Division

jaisankar@iicb.res.in