Credentials

Ph.D, Science (Structural Biology/ Biophysics),Indian Institute of Science [1997 – 2004]

MSc (Research), Interdisciplinary (physics & Chemistry),University of Mumbai [1993 – 1996], Studied at University Department of Chemical Technology (UDCT). 

BSc, Physics (Major), Chemistry and Mathematics,University of Mumbai [1989 – 1992], Studied at DG Ruparel College, Mahim, Mumbai.

Patents & Publications

1. Therapeutic Effect of Combinatorial Probiotics to Protect Intestinal Barrier Function, Rintu Das, Srabani Kar, Silpak Biswas, Umesh P Singh and Ena Ray Banerjee, EC Microbiology 9.2 (2017): 84-95
2. Tamarixetin 3-O-β-d-Glucopyranoside from Azadirachta indica Leaves: Gastroprotective Role through Inhibition of Matrix Metalloproteinase-9 Activity in Mice, Yadav DK, Bharitkar YP1, Hazra A1, Pal U, Verma S, Jana S, Singh UP, Maiti NC, Mondal NB, Swarnakar S., J Nat Prod. 2017 May 26;80(5):1347-1353
3. C11/C9 Helical Folding in αβ Hybrid Peptides Containing 1-Amino-cyclohexane acetic acid (β3, 3-Ac6c) Naiem Ahmad Wani, Srinivasarao Raghothama,Umesh Prasad Singh,* and Rajkishor Rai* Chem. Eur. J. 2017 DOI: 10.1002/chem.201700265
4. Incipient Twisted Ribbon Structure Stabilized by C 12 Helical Turns in γ 4 /α Hybrid Peptide Sudha Shankar · Naiem Ahmad Wani · Umesh Prasad Singh* · Rajkishor Rai* ChemistrySelect (2016), 1(13):3675-3678
5. Folded Structure Stabilized by C7, C10 and C12 Hydrogen Bonds in α/γ Hybrid Peptides Naiem Ahmad Wani, Vivek Kumar Gupta, Umesh Prasad Singh, Subrayashastry Aravinda, and Rajkishor Rai * ChemistrySelect (2016), 1, 1674 – 1677
6. Anti-Oxiflammatory profile of date extracts (Phoenix sylvestris) Rintu Das, Shinjini Mitra, Kaustab Mukherjee, Umesh P. Singh, Ena Ray Banerjee Biomedical Research and Therapy (2015) 2(6): 297-317
7. Anti-Oxidant and Anti-Inflammatory Activities of Different Varieties of Piper Leaf extracts (Piper betle L.), Rintu Das, Shinjini Mitra, Kaustab Mukherjee, Pramathadhip Paul, Umesh P. Singh, and Ena Ray Banerjee J Nutr Food Sci (2015), 5(5) 415. http://dx.doi.org/10.4172/2155-9600.1000415
8. Substituted fused tricyclic compounds, compositions and medicinal applications thereof Barawkar, Dinesh; Bende, Tanushree ; Zahler, Robert; Bandyopadhyay, Anish; Sarangthem, Robindro Singh; Doshi, Jignesh; Waman, Yogesh; Jadhav, Rushikesh, Singh, Umesh Prasad.United States Patent Application: US2014/0023614 A1 · Filed: 03/21/2012 · Published: 01/23/2014
9. BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF THAKKAR, Mahesh; KOUL, Summon; BHUNIYA, Debnath; SINGH, Umesh. WIPO Patent Application: WO/2013/157021 A1 · Filed: 04/18/2013 · Published: 10/24/2013
10. AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF KHARUL, Rajendra; BHUNIYA, Debnath;  MOOKHTIAR, Kasim A.; SINGH, Umesh; HAZARE, Atul ; PATIL, Satish; DATRANGE, Laxmikant; THAKKAR, Mahesh. WIPO Patent Application WO/2013/042139 A1 · Filed: 09/21/2012 · Published: 03/28/2013
11. DISCOVERY OF PYRAZOLE CARBOXYLIC ACIDS AS POTENT INHIBITORS OF RAT LONG CHAIN L-2-HYDROXY ACID OXIDASE, Dinesh A. Barawkar,§,* Anish Bandyopadhyay,§ Anil Deshpande,§ Summon Koul,§ Sachin Kandalkar,§ Pradeep Patil,§ Goraksha Khose,§ Samir Vyas,§ Mahesh Mone,§ Shubhangi Bhosale,§ Umesh Singh,§ Siddhartha De,§ Ashwin Meru,§ Jayasagar Gundu,§Anita Chugh,§ Venkata P. Palle,§ Kasim A. Mookhtiar,§ Joseph P. Vacca,† Prasun K. Chakravarty,† Ravi P. Nargund,† Samuel D. Wright,† Sophie Roy,†Michael P. Graziano,† Doris Cully,† Tian-Quan Cai,† Sheo B. Singh†.  J. Biog Med Chem Lett, Volume 22 (2012) 4341-4347.
12. Discovery of novel and potent  heterocyclic carboxylic acid derivatives as Protein Tyrosine Phosphatase 1B inhibitors, Sujay Basu, Uppuleti Viplava Prasad, Dinesh A. Barawkar, Suraj Menon, Siddhartha De, Meena S Patel,Venkata P Palle, Sachin Thorat, Umesh P. Singh, Yogesh Waman, Sanjay Niranjan, Vishal Pathade, Ashwani Gaur. Bioorganic & Medicinal Chemistry Letters, Volume 22 (2012), Pages 2843-2849)
13. Potent and Selective Inhibitors of Long Chain L-2-Hydroxy Acid Oxidase-2 Reduced Blood Pressure in DOCA-Salt Treated Rats. Dinesh A Barawkar, Ashwin Meru, Anish Bandyopadhyay, Abir Banerjee, Anil M Deshpande,Chandrashekhar Athare, Chandrasekhar Koduru, Goraksha Khose, Jayasagar Gundu, Koshu Mahajan, Pradeep Patil, Sachin R Kandalkar, Sanjay Niranjan, Shubhangi Bhosale, Siddhartha De, Sudit Mukhopadhyay, Sumit Chaudhary, Summon Koul, Umesh Singh, Anita Chugh, Venkata P. Palle, Kasim A Mookhtiar, Joseph Vacca, Prasun K Chakravarty, Ravi P. Nargund, Samuel, D. Wright, Sophie Roy, Michael P Graziano, Sheo Bux Singh, Doris Cully, and Tian-Quan Cai, ACS Med. Chem. Lett. (2011), 2, 919−923
14. Crystal structure of Onconase at 1.1-Å resolution. Insights into substrate binding and collective motion. Daniel E. Holloway, Umesh P. Singh, Kuslima Shogen and K. Ravi Acharya FEBS Journal 278 (2011) 4136–4149.
15. Structure of a Cyclic Water Tetramer in a Nucleotide Crystal Host and a Hypothetical Model for Water Cluster Growth. Umesh Prasad Singh* J. Mol Structure (2010) 983, 73-75.
16. Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes, Umesh P. Singh, Wojciech Ardelt, Shailendra K. Saxena, Daniel E. Holloway, Eugene Vidunas, Hung-Suen Lee, Abha Saxena, Kuslima Shogen and K. Ravi Acharya, J. Miol. Biol. (2007) 371, 93-111
17. Correlating Miscibility of PVC/PMMA blend with Polymer Chain Orientation.  Vineeta D. Deshpande and Umesh Singh*. J. Appl. Polym. Sci. (2006). 101, 624-630.
18. Ethyl 2-[N-(tert-butyloxycarbonyl)-L-alanylamino]-4-methyl-1, 3-thiazole-5-carboxylate reveals a trans orientation of the preceding amide N-H with respect to the thiazole-ring sulfur. Umesh Prasad Singh, Mini Thomas, T.P. Seshadri and Shantanu Bhattacharya.       Acta. Cryst. (2000) C56, 1482-1483 .